The Company Biomnigene
Biomnigene, a company specializing in molecular biology, offers high-quality genomic analysis services to companies, associations, and other organizations.

The team has occupied premises within the Maison des Microtechniques at TEMIS in Besançon since June 1, 2018. Composed of passionate engineers trained in the latest techniques, BIOMNIGENE is capable of addressing many of your questions and needs in terms of molecular biology, such as:
- DNA/RNA extraction from tissues, feces, cells, bacteria, urine, blood, saliva, semen…
- DNA amplification by PCR, cDNA from RNA by RT-PCR
- Quantification of gene expression by qPCR
- Purification of PCR products, DNA libraries, plasmids
- Quantification/detection of DNA, RNA, SNPs, microsatellites
- Quality control of DNA / RNA / cDNA, plasmids, DNA libraries
- Sequencing of nucleic acids, small genomes (bacteria), mRNA, transcriptomes, metagenomes, exomes using the SANGER method or Illumina high-throughput technology on MiSeq and iSeq100.
Specialized in genomic analysis, BIOMNIGENE is able, thanks to its expertise in both institutional and private sectors, to develop cutting-edge experimental protocols in accordance with Good Laboratory Practices. Its competencies also cover other areas of molecular biology such as the construction of recombinant plasmids and extend to cell biology.
The Biomnigene Team

Alexandre DOUABLIN
President - Sales
PhD in molecular and cell biology, with 7 years of experience as director of various laboratories in Europe, he serves as president of the company. Attentive to your projects, he is your primary contact for all commercial inquiries.

Cédric DIDIER
Administrative and Financial Manager
Holder of a Master's degree in business management and administration and a Master's degree in biotechnology, he manages the company and is your contact for administrative procedures.

Bénédicte ROGNON*
Scientific Project Manager
PhD in molecular and cell biology, her research experience primarily focused on the study of microorganisms makes her your preferred advisor for scientific questions related to health, agri-food, and the environment.

Fabrice BOUILLOUX*
Scientific Project Manager
PhD in molecular and cell biology, he specialized in the fields of developmental biology and transcription. Thanks to his knowledge of numerous models, he provides valuable assistance in the design and implementation of your projects.
*Also certified in Sanger sequencing, NGS library preparation, and the use of the latest generation Illumina instruments, they are your contacts for all scientific questions (advice, development, implementation...).


Publications and Citations
Age-Related Changes in the Gut Microbiota Modify Brain Lipid Composition
Albouery Mayssa, Buteau Bénédicte, Grégoire Stéphane, Cherbuy Claire, Pais de Barros Jean-Paul, Martine Lucy, Chain Florian, Cabaret Stéphanie, Berdeaux Olivier, Bron Alain M., Acar Niyazi, Langella Philippe, Bringer Marie-Agnès.
Frontiers in Cellular and Infection Microbiology. 2020: 9: 444.
Lactiplantibacillus plantarum WJL administration during pregnancy and lactation improves lipid profile, insulin sensitivity and gut microbiota diversity in dyslipidemic dams and protects male offspring against cardiovascular dysfunction in later life
Guimarães, Keyth Sulamitta de Lima and Braga, Valdir de Andrade and Noronha, Sylvana I. S. Rendeiro de and Costa, Whyara Karoline Almeida da and Makki, Kassem and Cruz, Josiane de Campos and Brandão, Larissa Ramalho and Chianca Junior, Deoclecio Alves and Meugnier, Emmanuelle and Leulier, François and Vidal, Hubert and Magnani, Marciane and de Brito Alves, José Luiz.
Food Funct. 2020: 11: 10: 8939-8950.
Gastrointestinal parasite burden in 4th-5th c. CE Florence highlighted by microscopy and paleogenetics
Roche Kévin, Capelli Nicolas, Pacciani Elsa, Lelli Paolo, Pallecchi Pasquino, Bianucci Raffaella, Le Bailly Matthieu.
Infection, Genetics and Evolution. 2021, Vol. 90, 104713
Effects of Fecal Microbiota Transplantation on Composition in Mice with CKD
Toxins. 2020, Vol. 12, 741
Metformin treatment for 8 days impacts multiple intestinal parameters in high-fat high-sucrose fed mice
Bravard, A., Gérard, C., Defois, C. et al.
Scientific Reports. 2021, Vol. 11, 16684
Feeding sites promoting wildlife-related tourism might highly expose the endangered Yunnan snub-nosed monkey (Rhinopithecus bieti) to parasite transmission.
Afonso, E., Fu, R., Dupaix, A. et al.
Scientific Reports. 2021, Vol. 11, 15817
Creating small food-habituated groups might alter genetic diversity in the endangered Yunnan snub-nosed monkey,
Eve Afonso, Rong Fu, Amaël Dupaix, Anne-Claude Goydadin, ZhongHua Yu, Dayong Li, Patrick Giraudoux, Li Li.
Global Ecology and Conservation. 2021, Vol. 26, e01422

Press Review
AER-BFC Brochure: Biotherapies and Bioproduction
Biomnigene is cited as a solution provider for biotherapy and bioproduction companies.
Témis News No. 59

Trace Ecrites News of March 11, 2019
Article following the 2019 Réseau Entreprendre award ceremony written by Christiane PERRUCHOT
In this article, you will find a section dedicated to Biomnigene and its founders, as well as a presentation of all the other award recipients from this cohort.
Read the full article at this link.
Grand Besançon Magazine No. 91

Est Républicain of March 7, 2019
Article on the Est Républicain newspaper website of March 7, 2019 following the 2019 award ceremony of Réseau Entreprendre Franche-Comté.
Biomnigene is now supported by the network.
Many thanks to them.
Find the article at the following link by clicking HERE
Témis News No. 56

Est Républicain of June 12, 2018

The Biomnigene Awards

2019
"Talents de l'Innovation" Award Winner
The BGE Franche-Comté talent competition was held on July 10, 2019.
Biomnigene received the 2019 "Talents de l'Innovation" award and a grant of €2,000 offered by Crédit Agricole de Franche-Comté.
Thanks to BGE Franche-Comté and all its partners.

2018
Réseau Entreprendre Award Winner
Biomnigene is now an award winner of Réseau Entreprendre Franche-Comté, supported by Mr. David HERIBAN from Percipio Robotics.
Below: Alexandre DOUABLIN holding the 2018 Réseau Entreprendre Franche-Comté award trophy, surrounded by Anthony JEANBOURQUIN (CCI du Doubs) and David HERIBAN (Percipio Robotics).

2017
Startup Weekend
Winner of the first Startup Weekend in Besançon, which took place at the Maison des Microtechniques from May 19 to 21, 2017.
Networks & Partners











Interested in Our Services?
Would you like additional information?
